Invention Grant
US08349811B2 Stable 6-methoxy-2′,3′-dideoxyguanosine, method for preparing the same and pharmaceutical composition containing the same
有权
稳定的6-甲氧基-2'，3'-二脱氧鸟苷，其制备方法以及含有它们的药物组合物
- Patent Title: Stable 6-methoxy-2′,3′-dideoxyguanosine, method for preparing the same and pharmaceutical composition containing the same
- Patent Title (中): 稳定的6-甲氧基-2'，3'-二脱氧鸟苷，其制备方法以及含有它们的药物组合物
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Application No.: US12743898Application Date: 2008-10-10
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Publication No.: US08349811B2Publication Date: 2013-01-08
- Inventor: Zhan Li , Haiyan Huang , Cailian Liu , Lixun Jiang
- Applicant: Zhan Li , Haiyan Huang , Cailian Liu , Lixun Jiang
- Applicant Address: CN Nanjing
- Assignee: Nanjing Changao Pharmaceutical Science & Technology Co., Limited
- Current Assignee: Nanjing Changao Pharmaceutical Science & Technology Co., Limited
- Current Assignee Address: CN Nanjing
- Agency: Gottlieb, Rackman & Reisman, P.C.
- Priority: CN200810019227 20080117
- International Application: PCT/CN2008/072646 WO 20081010
- International Announcement: WO2009/089702 WO 20090723
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H19/167 ; C07H19/173
Abstract:
A stable 6-methoxy-2′,3′-dideoxyguanosine comprises 6-30% water content. It is prepared by absorbing water in 6-methoxy-2′,3′-dideoxyguanosine with less than 6% water content at low temperature and certain humidity, or drying 6-methoxy-2′,3′-dideoxyguanosine with more than 30% water content. The stable 6-methoxy-2′,3′-dideoxyguanosine can be used to prepare medicament composition, and be used to manufacture pharmaceutical for fighting hepatitis B virus or HIV.
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