Invention Grant
- Patent Title: Treatment of cancer with bio and chemotherapy
- Patent Title (中): 用生化和化疗治疗癌症
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Application No.: US12528606Application Date: 2008-02-25
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Publication No.: US08349822B2Publication Date: 2013-01-08
- Inventor: John S. Yu
- Applicant: John S. Yu
- Applicant Address: US CA Los Angeles
- Assignee: Cedars-Sinai Medical Center
- Current Assignee: Cedars-Sinai Medical Center
- Current Assignee Address: US CA Los Angeles
- Agency: Nixon Peabody LLP
- Agent Linda B. Huber
- International Application: PCT/US2008/054918 WO 20080225
- International Announcement: WO2008/106408 WO 20080904
- Main IPC: A01N43/00
- IPC: A01N43/00 ; A01N43/42 ; A01N43/38 ; A61K31/33 ; A61K31/44 ; A61K31/405 ; C07C259/00
Abstract:
This invention relates to compositions and methods utilizing a chemotherapeutic drug and 6-bromoindirubin3′-oxime (BIO) for the treatment of cancer, including glioblastoma multiforme. The present invention demonstrates that BIO works synergistically with chemotherapeutic drugs to increase the cytotoxic effects of these drugs in glioma cells.
Public/Granted literature
- US20100068303A1 TREATMENT OF CANCER WITH BIO AND CHEMOTHERAPY Public/Granted day:2010-03-18
Information query
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