Invention Grant
US08349829B2 [4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl)-tetrahydro-pyran-3-yl]-methyl-amine derivatives as antibacterials
有权
[4-（1-氨基 - 乙基） - 环己基] - 甲基胺和[6-（1-氨基 - 乙基） - 四氢 - 吡喃-3-基] - 甲基 - 胺衍生物作为抗菌剂
![[4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl)-tetrahydro-pyran-3-yl]-methyl-amine derivatives as antibacterials](/docs/US/2013-01-08/US08349829B2/abs.jpg.600x600.jpg)
- Patent Title: [4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl)-tetrahydro-pyran-3-yl]-methyl-amine derivatives as antibacterials
- Patent Title (中): [4-（1-氨基 - 乙基） - 环己基] - 甲基胺和[6-（1-氨基 - 乙基） - 四氢 - 吡喃-3-基] - 甲基 - 胺衍生物作为抗菌剂
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Application No.: US12996360Application Date: 2009-06-02
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Publication No.: US08349829B2Publication Date: 2013-01-08
- Inventor: Christian Hubschwerlen , Georg Rueedi , Jean-Philippe Surivet , Cornelia Zumbrunn-Acklin
- Applicant: Christian Hubschwerlen , Georg Rueedi , Jean-Philippe Surivet , Cornelia Zumbrunn-Acklin
- Applicant Address: CH Allschwil
- Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee Address: CH Allschwil
- Agency: Hunton & Williams LLP
- Priority: WOPCT/IB2008/052157 20080603; WOPCT/IB2008/055421 20081218
- International Application: PCT/IB2009/052307 WO 20090602
- International Announcement: WO2009/147616 WO 20091210
- Main IPC: C07D513/04
- IPC: C07D513/04 ; C07D498/04 ; C07D405/06 ; A61K31/542 ; A61K31/5383 ; A61K31/4709
![[4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl)-tetrahydro-pyran-3-yl]-methyl-amine derivatives as antibacterials](/abs-image/US/2013/01/08/US08349829B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to antibacterial compounds of formula I wherein R1 represents alkoxy or halogen; U, V and W each represent CH, or one of U, V and W represents N and the others each represent CH; A represents CH2 or O; G is CH═CH-E wherein E represents a phenyl group mono- or di-substituted with halogen, or G is a group of one of the formulae hereafter wherein Z represent CH or N, Q represents O or S and K represents O or S; and salts of such compounds.
Public/Granted literature
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