Invention Grant
- Patent Title: Aryl aminopyridine PDE10 inhibitors
- Patent Title (中): 芳基氨基吡啶PDE10抑制剂
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Application No.: US13501130Application Date: 2010-10-26
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Publication No.: US08349830B2Publication Date: 2013-01-08
- Inventor: Michael J. Breslin , Christopher D. Cox , Izzat T. Raheem
- Applicant: Michael J. Breslin , Christopher D. Cox , Izzat T. Raheem
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme
- Current Assignee: Merck Sharp & Dohme
- Current Assignee Address: US NJ Rahway
- Agent Sylvia A. Ayler; Gerard M. Devlin
- International Application: PCT/US2010/054009 WO 20101026
- International Announcement: WO2011/053559 WO 20110505
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/497 ; A61K31/444 ; A61K31/4709 ; C07D413/14 ; C07D401/14 ; C07D471/14 ; C07D471/04 ; C07D215/14
Abstract:
The present invention is directed to aryl aminopyridine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
Public/Granted literature
- US20120196856A1 ARYL AMINOPYRIDINE PDE10 INHIBITORS Public/Granted day:2012-08-02
Information query
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