发明授权
- 专利标题： Aryl aminopyridine PDE10 inhibitors
- 专利标题（中）： 芳基氨基吡啶PDE10抑制剂
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申请号： US13501130申请日： 2010-10-26
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公开(公告)号： US08349830B2公开(公告)日： 2013-01-08
- 发明人: Michael J. Breslin , Christopher D. Cox , Izzat T. Raheem
- 申请人： Michael J. Breslin , Christopher D. Cox , Izzat T. Raheem
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme
- 当前专利权人： Merck Sharp & Dohme
- 当前专利权人地址： US NJ Rahway
- 代理商 Sylvia A. Ayler; Gerard M. Devlin
- 国际申请： PCT/US2010/054009 WO 20101026
- 国际公布： WO2011/053559 WO 20110505
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/497 ; A61K31/444 ; A61K31/4709 ; C07D413/14 ; C07D401/14 ; C07D471/14 ; C07D471/04 ; C07D215/14
摘要：
The present invention is directed to aryl aminopyridine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
公开/授权文献
- US20120196856A1 ARYL AMINOPYRIDINE PDE10 INHIBITORS 公开/授权日：2012-08-02
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