Invention Grant
- Patent Title: Salts of 4-aniline quinazoline derivative
- Patent Title (中): 4-苯胺喹唑啉衍生物的盐
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Application No.: US12527345Application Date: 2008-02-04
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Publication No.: US08349854B2Publication Date: 2013-01-08
- Inventor: Jianhui Guo , Yong Jiang
- Applicant: Jianhui Guo , Yong Jiang
- Applicant Address: CN
- Assignee: Shanghai Allist Pharmaceuticals, Inc.
- Current Assignee: Shanghai Allist Pharmaceuticals, Inc.
- Current Assignee Address: CN
- Agency: Myers Bigel Sibley & Sajovec, PA
- Priority: CN200710037557 20070214
- International Application: PCT/CN2008/000318 WO 20080204
- International Announcement: WO2008/098485 WO 20080821
- Main IPC: A61K31/517
- IPC: A61K31/517
Abstract:
The present invention relates to salt forms of N-{4-[3-chloro-4-(3-fluoro-benzyloxy)phenylamino]-quinazolin-6-yl}-acrylamide as exemplified by formula (I), methods of preparation thereof, pharmaceutical compositions comprising the same and their use thereof. The salt forms of the present invention, which possess excellent tumor inhibitory activity, good bioavailability and low toxicity in an animal body, are suitable for use of preparation of anti-tumor medicaments.
Public/Granted literature
- US20100168142A1 SALTS OF 4-ANILINE QUINAZOLINE DERIVATIVE Public/Granted day:2010-07-01
Information query
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