Invention Grant
- Patent Title: Polymorphs of erlotinib hydrochloride and method of preparation
- Patent Title (中): 盐酸厄洛替尼的多晶型物及其制备方法
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Application No.: US12672191Application Date: 2007-09-11
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Publication No.: US08349855B2Publication Date: 2013-01-08
- Inventor: Ramanadham Jyothi Prasad , Bhujanga rao Adibhatla Kali Satya , Nannapaneni Venkaiah Chowdary
- Applicant: Ramanadham Jyothi Prasad , Bhujanga rao Adibhatla Kali Satya , Nannapaneni Venkaiah Chowdary
- Applicant Address: IN Hyderabad, Andhra Pradesh
- Assignee: Natco Pharma Limited
- Current Assignee: Natco Pharma Limited
- Current Assignee Address: IN Hyderabad, Andhra Pradesh
- Agency: Merchant & Gould P.C.
- Priority: IN349/CHE/2007 20070221
- International Application: PCT/IN2007/000407 WO 20070911
- International Announcement: WO2008/102369 WO 20080828
- Main IPC: A61K31/517
- IPC: A61K31/517
Abstract:
The present invention relates to three novel crystalline forms of Erlotinib hydrochloride and method of preparation thereof. Erlotinib hydrochloride is N-(3-ethynylphenyl)-6,7-bis(2-methoxy ethoxy)-4-quinazolinamine hydrochloride of formula-(I). The present invention provides stable novel crystalline forms of Erlotinib hydrochloride designated as Form-M, Form-N and Form-P, and processes for the preparation of the same. Erlotinib hydrochloride can be used as medicament for the treatment of hyperproliferative disorders, such as cancers, in humans.
Public/Granted literature
- US20100261738A1 NOVEL POLYMORPHS OF ERLOTINIB HYDROCHLORIDE AND METHOD OF PREPARATION Public/Granted day:2010-10-14
Information query
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