Invention Grant
US08350026B2 VEGF-2 receptor and protein tyrosine kinase inhibitors and pharmaceutical use thereof
有权
VEGF-2受体和蛋白酪氨酸激酶抑制剂及其药物用途
- Patent Title: VEGF-2 receptor and protein tyrosine kinase inhibitors and pharmaceutical use thereof
- Patent Title (中): VEGF-2受体和蛋白酪氨酸激酶抑制剂及其药物用途
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Application No.: US13058797Application Date: 2009-08-27
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Publication No.: US08350026B2Publication Date: 2013-01-08
- Inventor: Jakob Felding , Xifu Liang , Anne Marie Horneman , Tina Dahlerup Poulsen , Jens Christian Højland Larsen
- Applicant: Jakob Felding , Xifu Liang , Anne Marie Horneman , Tina Dahlerup Poulsen , Jens Christian Højland Larsen
- Applicant Address: DK Ballerup
- Assignee: Leo Pharma A/S
- Current Assignee: Leo Pharma A/S
- Current Assignee Address: DK Ballerup
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: DK200801449 20081017
- International Application: PCT/DK2009/000190 WO 20090827
- International Announcement: WO2010/022725 WO 20100304
- Main IPC: C07D213/72
- IPC: C07D213/72 ; C07D405/12 ; C07D413/06 ; C07D413/12
Abstract:
The invention relates to compounds of general formula (I) wherein W, D, E, G, J, L, R1, R2, R3, R4, R5 and Y are as defined herein, and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for treating diseases associated with deregulated angiogenesis, such as cancer and skin and eye diseases.
Public/Granted literature
- US20110190282A1 NOVEL VEGF-2 RECEPTOR AND PROTEIN TYROSINE KINASE INHIBITORS AND PHARMACEUTICAL USE THEREOF Public/Granted day:2011-08-04
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