Invention Grant
- Patent Title: Antagonists of the TRPV1 receptor and uses thereof
- Patent Title (中): TRPV1受体的拮抗剂及其用途
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Application No.: US13249010Application Date: 2011-09-29
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Publication No.: US08350083B2Publication Date: 2013-01-08
- Inventor: Arthur R. Gomtsyan , Robert G. Schmidt , Jerome F. Daanen , Erol K. Bayburt , Chih-hung Lee , Steven P. Latshaw
- Applicant: Arthur R. Gomtsyan , Robert G. Schmidt , Jerome F. Daanen , Erol K. Bayburt , Chih-hung Lee , Steven P. Latshaw
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Main IPC: C07C275/00
- IPC: C07C275/00 ; C07D215/44
Abstract:
The present application is directed to compounds that are TRPV1 antagonists and have formula (I) wherein variables Ar1, L1, R1, R2, R3, R4, R5, Y1, Y2, and Y3, are as defined in the description, which are useful for treating disorders caused by or exacerbated by vanilloid receptor activity.
Public/Granted literature
- US20120022103A1 ANTAGONISTS OF THE TRPV1 RECEPTOR AND USES THEREOF Public/Granted day:2012-01-26
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