A dereverberation and noise reduction method adapted for a microphone array and an apparatus using the same are proposed. The microphone array receives a plurality of audio signals from an audio source. The dereverberation and noise reduction method includes the following steps. The received audio signals are processed by a beamforming processing, and a first audio signal is generated. Besides, the received audio signals are processed by a suppression processing, and a suppression audio vector is generated. Further, suppression audio vector is processed by an adaptive filtering processing, and a second audio signal is generated. In addition, the second audio signal is subtracted from the first audio signal to acquire an audio output signal, where parameters of the adaptive filtering processing are adjusted according to a feedback of the audio output signal.