Provided is a method of controlling memory access. In a system including a first layer element executed in a privileged mode having a first priority of permission to access the entire region of a memory and second and third layer elements executed in an unprivileged mode having a second priority of permission to access a partial region of the memory, the method of controlling memory access determines whether the memory is accessible for each page that is an address space unit, based on which mode a layer element currently accessing the memory is executed in between the privileged mode and the unprivileged mode; and determines whether the memory is accessible based on which one of the first, second and third layer elements corresponds to a domain currently being attempted to be accessed from among a plurality of domains of the memory. Accordingly, a memory domain allocated to a guest operating system kernel is effectively protected from an application executed in the unprivileged mode in which the guest operating system kernel is executed.