In one embodiment, the present invention includes power control logic for squelch detection circuitry to enable selective enabling of one or more squelch detection circuits of an interconnect interface in a low power mode. The logic may include a squelch mode control register to select a first mode or a second mode of power control, a second register coupled to the squelch mode control register to receive software settings to indicate which squelch detect circuit(s) to disable in a low power state of the interconnect, and a detector to dynamically detect a logical lane zero of the interconnect in the second mode. Other embodiments are described and claimed.