The inter-clock domain data transfer FIFO circuit provides a circuit that transfers data between two clock domains of unrelated frequencies. The gate count is kept relatively low, thereby allowing data transfer between the two clock domains at one data item per cycle of the lower of the two frequencies. Depending on the frequency difference between the data producer and consumer, the initial latency could be as low as a fraction of a cycle and no more than two cycles of the consumer's clock. The operation of the data transfer FIFO circuit has been verified using gate-level simulations for several ratios of clock frequencies.