发明授权
US08354401B2 Oxazolidinone amide aromatic compounds for supressing MMP-9 production
有权
用于抑制MMP-9产生的恶唑烷酮酰胺芳香族化合物
- 专利标题： Oxazolidinone amide aromatic compounds for supressing MMP-9 production
- 专利标题（中）： 用于抑制MMP-9产生的恶唑烷酮酰胺芳香族化合物
-
申请号： US13126119申请日： 2009-10-27
-
公开(公告)号： US08354401B2公开(公告)日： 2013-01-15
- 发明人: Seigo Ishibuchi , Hidemasa Hikawa , Akiko Tarao , Jun-ichi Endoh , Kunitomo Adachi , Kazuhiro Maeda , Kaoru Tashiro
- 申请人： Seigo Ishibuchi , Hidemasa Hikawa , Akiko Tarao , Jun-ichi Endoh , Kunitomo Adachi , Kazuhiro Maeda , Kaoru Tashiro
- 申请人地址： JP Osaka-shi
- 专利权人： Mitsubishi Tanabe Pharma Corporation
- 当前专利权人： Mitsubishi Tanabe Pharma Corporation
- 当前专利权人地址： JP Osaka-shi
- 代理机构： Leydig, Voit & Mayer, Ltd.
- 优先权： JP2008-276147 20081027
- 国际申请： PCT/JP2009/068386 WO 20091027
- 国际公布： WO2010/050461 WO 20100506
- 主分类号： A01N43/62
- IPC分类号： A01N43/62 ; A61K31/55
摘要：
Provided are a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2, as well as a prophylactic/therapeutic drug for autoimmune diseases or osteoarthritis. An amide derivative represented by the following formula (I) wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, or a hydrate or solvate thereof.
公开/授权文献
- US20110263571A1 NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE 公开/授权日：2011-10-27
信息查询
IPC分类:
