发明授权
- 专利标题: Pyrimidine inhibitors of kinase activity
- 专利标题(中): 嘧啶抑制剂激酶活性
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申请号: US12788008申请日: 2010-05-26
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公开(公告)号: US08354422B2公开(公告)日: 2013-01-15
- 发明人: Richard F. Clark , Randy L. Bell , Nwe Y. Ba-maung , Scott A. Erickson , Steve D. Fidanze , Robert A. Mantei , George S. Sheppard , Bryan K. Sorensen , Gary T. Wang , Jieyi Wang
- 申请人: Richard F. Clark , Randy L. Bell , Nwe Y. Ba-maung , Scott A. Erickson , Steve D. Fidanze , Robert A. Mantei , George S. Sheppard , Bryan K. Sorensen , Gary T. Wang , Jieyi Wang
- 申请人地址: US IL Abbott Park
- 专利权人: Abbott Laboratories Inc.
- 当前专利权人: Abbott Laboratories Inc.
- 当前专利权人地址: US IL Abbott Park
- 代理商 Glen J. Gesicki
- 主分类号: C07D403/14
- IPC分类号: C07D403/14 ; C07D413/14 ; A61K31/5377 ; A61K31/506
摘要:
The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R.
公开/授权文献
- US20100305126A1 Pyrimidine Inhibitors of Kinase Activity 公开/授权日:2010-12-02
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