发明授权
- 专利标题： Peptide binding to methylated DNA
- 专利标题（中）： 肽结合甲基化DNA
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申请号： US13502272申请日： 2010-10-15
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公开(公告)号： US08354497B2公开(公告)日： 2013-01-15
- 发明人: Akimitsu Okamoto , Akiko Nomura
- 申请人： Akimitsu Okamoto , Akiko Nomura
- 申请人地址： JP Wako-shi, Saitama
- 专利权人： Riken
- 当前专利权人： Riken
- 当前专利权人地址： JP Wako-shi, Saitama
- 代理机构： Leydig, Voit & Mayer, Ltd.
- 优先权： JP2009-239657 20091016
- 国际申请： PCT/JP2010/068194 WO 20101015
- 国际公布： WO2011/046214 WO 20110421
- 主分类号： C07K14/00
- IPC分类号： C07K14/00
摘要：
The present invention aims to provide a tool etc. capable of detecting a methylated region of a DNA in a short time, in a labor-saving manner and without being limited by nucleotide sequences, and further capable of quantifying the methylation. The present invention provides a peptide containing a metal finger motif and a tyrosine derivative in a helix forming part of the motif, which recognizes and binds to a methylated region of a double stranded DNA.
公开/授权文献
- US20120238038A1 PEPTIDE BINDING TO METHYLATED DNA 公开/授权日：2012-09-20
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