发明授权
US08354520B2 Composition and method for treating atherosclerosis, method for determining if a subject has atherosclerosis and method of screening an anti-atherosclerotic drug
有权
用于治疗动脉粥样硬化的组合物和方法,用于确定受试者是否具有动脉粥样硬化的方法和筛选抗动脉粥样硬化药物的方法
- 专利标题: Composition and method for treating atherosclerosis, method for determining if a subject has atherosclerosis and method of screening an anti-atherosclerotic drug
- 专利标题(中): 用于治疗动脉粥样硬化的组合物和方法,用于确定受试者是否具有动脉粥样硬化的方法和筛选抗动脉粥样硬化药物的方法
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申请号: US12635178申请日: 2009-12-10
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公开(公告)号: US08354520B2公开(公告)日: 2013-01-15
- 发明人: Suh-Hang Hank Juo , Yung-Song Wang
- 申请人: Suh-Hang Hank Juo , Yung-Song Wang
- 申请人地址: TW Kaohsiung
- 专利权人: Kaohsiung Medical University
- 当前专利权人: Kaohsiung Medical University
- 当前专利权人地址: TW Kaohsiung
- 代理机构: Pai Patent & Trademark Law Firm
- 代理商 Chao-Chang David Pai
- 主分类号: C07H21/04
- IPC分类号: C07H21/04
摘要:
The invention provides a method for determining if a subject has atherosclerosis, including: determining an endogenous microRNA-195 expression level of a subject suspected of having atherosclerosis; and comparing the endogenous microRNA-195 expression level of the subject with an endogenous microRNA-195 expression level of a normal group, wherein an increase in the endogenous microRNA-195 expression level of the subject as compared to the endogenous microRNA-195 expression level of the normal group indicates that the subject has atherosclerosis.
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