发明授权
US08361954B2 Use of IL-28 and IL-29 to treat cancer and autoimmune disorders
有权
使用IL-28和IL-29治疗癌症和自身免疫性疾病
- 专利标题: Use of IL-28 and IL-29 to treat cancer and autoimmune disorders
- 专利标题(中): 使用IL-28和IL-29治疗癌症和自身免疫性疾病
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申请号: US12818050申请日: 2010-06-17
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公开(公告)号: US08361954B2公开(公告)日: 2013-01-29
- 发明人: Sean Doyle , Kevin M. Klucher , Pallavur V. Sivakumar , Wayne R. Kindsvogel , Chung Chan
- 申请人: Sean Doyle , Kevin M. Klucher , Pallavur V. Sivakumar , Wayne R. Kindsvogel , Chung Chan
- 申请人地址: US WA Seattle
- 专利权人: ZymoGenetics, Inc.
- 当前专利权人: ZymoGenetics, Inc.
- 当前专利权人地址: US WA Seattle
- 代理商 Bing Hai; Brian J. Walsh
- 主分类号: A01N37/18
- IPC分类号: A01N37/18
摘要:
Methods for treating patients with cancer and autoimmune disorders using IL-28 and IL-29 molecules. The IL-28 and IL-29 molecules include polypeptides that have homology to the human IL-28 or IL-29 polypeptide sequence and proteins fused to a polypeptide with IL-28 and IL-29 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer and/or autoimmune therapeutics.