Invention Grant
- Patent Title: Uses of FGF21 polypeptides comprising two or more mutations
- Patent Title (中): 包含两个或多个突变的FGF21多肽的用途
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Application No.: US13328028Application Date: 2011-12-16
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Publication No.: US08361963B2Publication Date: 2013-01-29
- Inventor: Edward John Belouski , Murielle Marie Ellison , Agnes Eva Hamburger , Randy Ira Hecht , Yue-Sheng Li , Mark Leo Michaels , Jeonghoon Sun , Jing Xu
- Applicant: Edward John Belouski , Murielle Marie Ellison , Agnes Eva Hamburger , Randy Ira Hecht , Yue-Sheng Li , Mark Leo Michaels , Jeonghoon Sun , Jing Xu
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Mary K. Hehman; John Lamerdin
- Main IPC: A61K38/18
- IPC: A61K38/18 ; C07K14/50
Abstract:
The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.
Public/Granted literature
- US20120093815A1 FGF21 MUTANTS AND USES THEREOF Public/Granted day:2012-04-19
Information query
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