- 专利标题: Azetidinyl diamides as monoacylglycerol lipase inhibitors
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申请号: US12765076申请日: 2010-04-22
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公开(公告)号: US08367653B2公开(公告)日: 2013-02-05
- 发明人: Haiyan Bian , Kristen Chevalier , Jose Clemente , Pete Connolly , Chris Flores , Shu-Chen Lin , Li Liu , John Mabus , Mark MacIelag , Mark McDonnell , Philip Pitis , Yue-Mei Zhang , Sui-Po Zhang , Bin Zhu
- 申请人: Haiyan Bian , Kristen Chevalier , Jose Clemente , Pete Connolly , Chris Flores , Shu-Chen Lin , Li Liu , John Mabus , Mark MacIelag , Mark McDonnell , Philip Pitis , Yue-Mei Zhang , Sui-Po Zhang , Bin Zhu
- 申请人地址: BE Beerse
- 专利权人: Janssen Pharmaceutica NV
- 当前专利权人: Janssen Pharmaceutica NV
- 当前专利权人地址: BE Beerse
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; C07D401/12 ; C07D403/14 ; C07D417/12 ; C07D417/14 ; C07D487/04 ; C07D495/04
摘要:
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.
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