A tire pressure sensor is provided having a housing, a pressure transducer within the housing electronically coupled to a transmitter, a battery within the housing connected to deliver electrical power to the pressure transducer and to the transmitter, and a pressurized compartment within the housing bounded at least partially by a flexible membrane. A first conduit extends from the pressure transducer to the compartment. An inlet port extends through the housing to allow pressurized air within the tire to contact the membrane. In particular embodiments, the pressure transducer, transmitter and battery are rubber coated and encapsulated with epoxy.