Invention Grant
US08377905B2 Stable crystal of 1-(2′-cyano-2′-deoxy-β-D-arabinofuranosyl)cytosine monohydrochloride
有权
1-（2'-氰基-2'-脱氧-β-阿拉伯呋喃糖基）胞嘧啶一盐酸盐的稳定晶体
- Patent Title: Stable crystal of 1-(2′-cyano-2′-deoxy-β-D-arabinofuranosyl)cytosine monohydrochloride
- Patent Title (中): 1-（2'-氰基-2'-脱氧-β-阿拉伯呋喃糖基）胞嘧啶一盐酸盐的稳定晶体
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Application No.: US13264111Application Date: 2010-05-14
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Publication No.: US08377905B2Publication Date: 2013-02-19
- Inventor: Shotaro Watanabe , Takahiro Hatakeyama
- Applicant: Shotaro Watanabe , Takahiro Hatakeyama
- Applicant Address: JP Tokushima-shi
- Assignee: Delta-Fly Pharma, Inc.
- Current Assignee: Delta-Fly Pharma, Inc.
- Current Assignee Address: JP Tokushima-shi
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2009-118726 20090515
- International Application: PCT/JP2010/003261 WO 20100514
- International Announcement: WO2010/131475 WO 20101118
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H19/00 ; C07H19/048 ; C07H19/06
Abstract:
Disclosed is a stable crystal of 1-(2′-cyano-2′-deoxy-β-D-arabinofuranosyl)cytosine monohydrochloride. There is provided a crystal of 1-(2′-cyano-2′-deoxy-β-D-arabinofuranosyl)cytosine monohydrochloride having characteristic peaks at 13.7°, 15.7°, 16.0°, 18.6°, 20.3°, and 22.7° as diffraction angles (2θ±0.1°) measured by powder X-ray diffraction, and having a melting point of 192° C. to 197° C.
Public/Granted literature
- US20120029182A1 NOVEL STABLE CRYSTAL OF 1-(2'-CYANO-2'-DEOXY-BETA-D-ARABINOFURANOSYL)CYTOSINE MONOHYDROCHLORIDE Public/Granted day:2012-02-02
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