发明授权
US08377972B2 Use of quaternary pyridinium compounds for vasoprotection and/or hepatoprotection
失效
使用季铵吡啶化合物进行血管保护和/或肝保护
- 专利标题： Use of quaternary pyridinium compounds for vasoprotection and/or hepatoprotection
- 专利标题（中）： 使用季铵吡啶化合物进行血管保护和/或肝保护
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申请号： US13011364申请日： 2011-01-21
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公开(公告)号： US08377972B2公开(公告)日： 2013-02-19
- 发明人: Andrzej Marcinek , Stefan Chłopicki , Jerzy Gȩbicki , Jan Adamus
- 申请人： Andrzej Marcinek , Stefan Chłopicki , Jerzy Gȩbicki , Jan Adamus
- 申请人地址： PL Cracow
- 专利权人： Trigendo Sp. zo.o.
- 当前专利权人： Trigendo Sp. zo.o.
- 当前专利权人地址： PL Cracow
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 优先权： PL381862 20070228
- 主分类号： A61K31/44
- IPC分类号： A61K31/44
摘要：
The invention relates to a method for the treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury comprising the administration to a patient in a need of such treatment or prevention of a therapeutically or prophylactically effective amount of a compound selected from the group consisting of: wherein R represents hydrogen atom, CH3, OH, pyridyl (C5H4N), 1-methylpyridyl (C5H4N—CH3) or pyridyl substituted with hydroxy group ((OH)C5H3N), and X represents a physiologically acceptable counterion.
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