发明授权
- 专利标题： Collectin fusion proteins comprising TNF or trail
- 专利标题（中）： 包含TNF或追踪的集合蛋白融合蛋白
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申请号： US12668188申请日： 2008-07-10
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公开(公告)号： US08383774B2公开(公告)日： 2013-02-26
- 发明人: Oliver Hill , Christian Gieffers , Meinolf Thiemann , Marcus Branschädel
- 申请人： Oliver Hill , Christian Gieffers , Meinolf Thiemann , Marcus Branschädel
- 申请人地址： DE Heidelberg
- 专利权人： Apogenix GmbH
- 当前专利权人： Apogenix GmbH
- 当前专利权人地址： DE Heidelberg
- 代理机构： Perkins Coie LLP.
- 代理商 Viola T. Kung
- 优先权： EP07013506 20070710
- 国际申请： PCT/EP2008/005644 WO 20080710
- 国际公布： WO2009/007120 WO 20090115
- 主分类号： C07K1/00
- IPC分类号： C07K1/00 ; C07K14/00 ; C07K17/00 ; C07K16/00 ; C12P21/06 ; C12N1/20 ; C12N15/00 ; C12N5/00 ; C12N5/02 ; C12N15/74 ; C07H21/04
摘要：
The present invention refers to a fusion protein comprising a TNF-superfamily (TNFSF) cytokine or a receptor binding domain thereof fused to a collectin trimerization domain, to a nucleic acid molecule encoding the fusion protein, and to a cell comprising the nucleic acid molecule. The fusion protein is present as a trimeric complex or as an oligomer thereof. The fusion protein, the nucleic acid, and the cell is suitable as pharmaceutical composition or for therapeutic, diagnostic and/or research applications.
公开/授权文献
- US20100199364A1 TNF SUPERFAMILY COLLECTIN FUSION PROTEINS 公开/授权日：2010-08-05