A differential radio frequency signal transmitter is provided. The differential radio frequency signal transmitter includes an oscillator, a modulator and an amplifier module. The oscillator generates a pair of differential oscillation signals. The modulator generates a pair of differential modulated signals according to an input signal and the pair of differential oscillation signals. The input signal is a digital signal. When the input signal is at a first state, the modulator outputs the pair of differential oscillation signals as the pair of differential modulated signals, and when the input signal is at a second state, the modulator outputs a constant voltage signal as the pair of differential modulated signals. The amplifier module receives and amplifies the pair of differential modulated signals and generates a pair of differential radio frequency signals, accordingly.