发明授权
- 专利标题： Sequential delivery of immunogenic molecules via adenovirus and adeno-associated virus-mediated administrations
- 专利标题（中）： 通过腺病毒和腺相关病毒介导的给药顺序递送免疫原性分子
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申请号： US11587543申请日： 2005-04-27
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公开(公告)号： US08394386B2公开(公告)日： 2013-03-12
- 发明人: James M. Wilson
- 申请人： James M. Wilson
- 申请人地址： US PA Philadelphia
- 专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Howson & Howson LLP
- 国际申请： PCT/US2005/014556 WO 20050427
- 国际公布： WO2006/078279 WO 20060727
- 主分类号： A61K39/23
- IPC分类号： A61K39/23 ; A61K39/116 ; C12Q1/70
摘要：
An immunogenic regimen is provided. The regimen involves sequential administration of a recombinant adenoviral vector and a recombinant adeno-associated viral vector, each of which delivers a heterologous expression cassette encoding the same immunogenic product, or a cross-reactive immunogenic product. Also provided are products containing the vectors for use in the regimen of the invention.
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