Invention Grant
US08394776B2 Use of ursolic acid saponin,oleanolic acid saponin in preparation of increasing leucocytes and/or platelet medicine
有权
使用熊果酸皂苷，齐墩果酸皂苷制备增加的白细胞和/或血小板药物
- Patent Title: Use of ursolic acid saponin,oleanolic acid saponin in preparation of increasing leucocytes and/or platelet medicine
- Patent Title (中): 使用熊果酸皂苷，齐墩果酸皂苷制备增加的白细胞和/或血小板药物
-
Application No.: US12523314Application Date: 2008-01-16
-
Publication No.: US08394776B2Publication Date: 2013-03-12
- Inventor: Bing Guang , Junjian Liu , Guangxin Dong , Xiangyang Peng , Xiaoxia Gong , Zhen Huang , Meirong Zhou , Wei Zhan , Jufang Yan , Yu Huang , Dongguang Qin , Jianxin Ji , Bogang Li
- Applicant: Bing Guang , Junjian Liu , Guangxin Dong , Xiangyang Peng , Xiaoxia Gong , Zhen Huang , Meirong Zhou , Wei Zhan , Jufang Yan , Yu Huang , Dongguang Qin , Jianxin Ji , Bogang Li
- Applicant Address: CN Sichuan
- Assignee: Chengdu Di'Ao Jiuhong Pharmaceutical Factor
- Current Assignee: Chengdu Di'Ao Jiuhong Pharmaceutical Factor
- Current Assignee Address: CN Sichuan
- Agency: Occhiuti Rohlicek & Tsao LLP
- Priority: CN200710048277 20070116; CN200710048278 20070116
- International Application: PCT/CN2008/000107 WO 20080116
- International Announcement: WO2008/086739 WO 20080724
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70
Abstract:
The invention provides the use of ursolic acid saponin and oleanolic acid saponin of formula (I) in preparing medicaments for increasing leucocytes and/or platelets. The invention also provides a pharmaceutical composition containing the same compound. The invention utilizes the cheap and accessible ursolic acid and oleanolic acid which are widely present in natural plants as raw materials, introduces monosaccharyls or oligosaccharyls by structural modification. It is proved by pharmacological tests that the compound of formula (I) have an activity of obviously increasing leucocytes and/or platelets.
Public/Granted literature
Information query
IPC分类:
