- 专利标题： Phosphonic acid compounds as inhibitors of serine proteases
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申请号： US12288920申请日： 2008-10-24
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公开(公告)号： US08394804B2公开(公告)日： 2013-03-12
- 发明人: Michael N. Greco , Harold R. Almond, Jr. , Lawrence de Garavilla , Michael J. Hawkins , Michael J. Humora , Yun Qian , Donald Gilmore Walker , Sergio Cesco-Cancian , Christopher Norman Nilsen , Mitul N. Patel , Kirk Leonerd Sorgi , Eugene Powell
- 申请人： Michael N. Greco , Harold R. Almond, Jr. , Lawrence de Garavilla , Michael J. Hawkins , Michael J. Humora , Yun Qian , Donald Gilmore Walker , Sergio Cesco-Cancian , Christopher Norman Nilsen , Mitul N. Patel , Kirk Leonerd Sorgi , Eugene Powell
- 申请人地址： BE
- 专利权人： Janssen Pharmaceutica N.V.
- 当前专利权人： Janssen Pharmaceutica N.V.
- 当前专利权人地址： BE
- 代理商 Yuriy P. Stercho
- 主分类号： A61K31/4965
- IPC分类号： A61K31/4965 ; C07D241/04 ; C07D295/00
摘要：
The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders.
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