发明授权
US08394967B2 Antioxidant inflammation modulators: C-17 homologated oleanolic acid derivatives
有权
抗氧化剂炎症调节剂:C-17同系齐墩果酸衍生物
- 专利标题: Antioxidant inflammation modulators: C-17 homologated oleanolic acid derivatives
- 专利标题(中): 抗氧化剂炎症调节剂:C-17同系齐墩果酸衍生物
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申请号: US13033475申请日: 2011-02-23
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公开(公告)号: US08394967B2公开(公告)日: 2013-03-12
- 发明人: Xin Jiang , Xiaofeng Liu , Jack Greiner , Stephen S. Szucs , Melean Visnick
- 申请人: Xin Jiang , Xiaofeng Liu , Jack Greiner , Stephen S. Szucs , Melean Visnick
- 申请人地址: US TX Irving
- 专利权人: Reata Pharmaceuticals, Inc.
- 当前专利权人: Reata Pharmaceuticals, Inc.
- 当前专利权人地址: US TX Irving
- 代理机构: Parker Highlander PLLC
- 主分类号: C07C255/47
- IPC分类号: C07C255/47 ; C07D209/48 ; C07D257/04 ; C07D261/08
摘要:
This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.