A channelized amplification system and method for mitigating non-linear amplification effects and controlling spectral re-growth is disclosed. A channelized amplifier system includes a frequency divider, a plurality of distributors coupled to the frequency divider, and a plurality of amplification modules coupled to the plurality of distributors. Each of the plurality of amplification modules includes a plurality of channelized non-linear amplifiers, a frequency combiner having a plurality of band-pass filters and coupled to the plurality of channelized non-linear amplifiers, and a band-pass filter coupled to the frequency combiner.