An ultrasound diagnostic apparatus includes: transmission and reception signal lines that send transmission and reception signals of ultrasound to a plurality of ultrasound transducers; signal determining portions near the ultrasound transducers and determine a selection signal for selecting an ultrasound transducer to be driven or a readout signal for reading out the selection signal, the selection signal being sent out in synchronization with a transmission signal for forming the transmission and reception signal, and couple the ultrasound transducer to be driven with the transmission and reception signal line according to a result of the determination; and direct current blocking/clipping circuits that block a direct current bias component superimposed on the transmission and reception signal and sent via the transmission and reception signal line, and clip a waveform with large amplitude. The transmission and reception signal line sends the transmission and reception signal with the selection signal or the readout signal.