Invention Grant
- Patent Title: Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
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Application No.: US13217515Application Date: 2011-08-25
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Publication No.: US08404893B2Publication Date: 2013-03-26
- Inventor: Heinz-Werner Kleemann
- Applicant: Heinz-Werner Kleemann
- Applicant Address: DE Frankfurt AM Main
- Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee Address: DE Frankfurt AM Main
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: DE10222192 20020518
- Main IPC: C07C277/00
- IPC: C07C277/00 ; C07C279/22 ; C07C309/89
Abstract:
Pentafluorosulfanylbenzoylguanidines of the formula I and II in which R1 to R4 have the meanings stated in the claims, are suitable as antiarrhythmic medicaments with a cardioprotective component for the prophylaxis of infarction and treatment of infarction and for the treatment of angina pectoris. They also inhibit preventively the pathophysiological processes associated with the development of ischemia-induced damage, especially in the triggering of ischemia-induced cardiac arrhythmias.
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