A printing apparatus and ink discharge failure detection method capable of precisely detecting temperature information corresponding to each nozzle are provided. Temperatures of respective electrothermal transducers (heaters) are measured on the basis of outputs from a plurality of sensors corresponding to the respective heaters. The temperatures of the heaters at a predetermined timing during a printing operation are predicted on the basis of the temperature change profiles of the respective heaters that are generated by energizing the heaters. A plurality of thresholds corresponding to nozzle states are generated on the basis of the predicted temperatures and the driving conditions of an inkjet printhead, and it is controlled to execute temperature measurement at the predetermined timing. A temperature measured under the control is compared with the respective generated thresholds, and the nozzle state is identified on the basis of the comparison results.