发明授权
US08426404B2 Pyrimidine-substituted benzimidazole derivatives as protein kinase inhibitors
失效
嘧啶取代的苯并咪唑衍生物作为蛋白激酶抑制剂
- 专利标题: Pyrimidine-substituted benzimidazole derivatives as protein kinase inhibitors
- 专利标题(中): 嘧啶取代的苯并咪唑衍生物作为蛋白激酶抑制剂
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申请号: US11915148申请日: 2006-06-30
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公开(公告)号: US08426404B2公开(公告)日: 2013-04-23
- 发明人: Guobao Zhang , Pingda Ren , Xia Wang , Nathanel Gray , Taebo Sim
- 申请人: Guobao Zhang , Pingda Ren , Xia Wang , Nathanel Gray , Taebo Sim
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 代理商 Scott W. Reid
- 国际申请: PCT/US2006/025706 WO 20060630
- 国际公布: WO2007/005673 WO 20070111
- 主分类号: A61K31/535
- IPC分类号: A61K31/535 ; C07D419/00
摘要:
The invention provides a novel class of compounds having Formula Ia, wherein each variable is as defined; and pharmaceutical compositions comprising such compounds and methods of using such compounds for inhibiting c-Src, FGFR3, KDR and/or Lck.