Invention Grant
US08431532B2 FZD8 extracellular domains and FZD8 extracellular domain fusion molecules and treatments using same
有权
FZD8细胞外结构域和FZD8细胞外结构域融合分子及其处理方法
- Patent Title: FZD8 extracellular domains and FZD8 extracellular domain fusion molecules and treatments using same
- Patent Title (中): FZD8细胞外结构域和FZD8细胞外结构域融合分子及其处理方法
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Application No.: US13169900Application Date: 2011-06-27
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Publication No.: US08431532B2Publication Date: 2013-04-30
- Inventor: Thomas Brennan , Ernestine Lee , Steven Smith
- Applicant: Thomas Brennan , Ernestine Lee , Steven Smith
- Applicant Address: US CA South San Francisco
- Assignee: Five Prime Therepeutics, Inc.
- Current Assignee: Five Prime Therepeutics, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Casimir Jones, S.C.
- Main IPC: A61K38/17
- IPC: A61K38/17
Abstract:
Methods of treatment using Fzd8 extracellular domains (ECDs), Fzd8 ECD fusion molecules, and/or antibodies that bind Fzd8 are provided. Such methods include, but are not limited to, methods of treating obesity and obesity-related conditions. Fzd8 ECDs and Fzd8 ECD fusion molecules are also provided. Polypeptide and polynucleotide sequences, vectors, host cells, and compositions comprising or encoding such molecules are provided. Methods of making and using Fzd8 ECDs, Fzd8 ECD fusion molecules, and antibodies that bind Fzd8 are also provided.
Public/Granted literature
- US20120003222A1 FZD8 EXTRACELLULAR DOMAINS AND FZD8 EXTRACELLULAR DOMAIN FUSION MOLECULES AND TREATMENTS USING SAME Public/Granted day:2012-01-05
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