- 专利标题： Guanidine compounds, and use thereof as binding partners for 5-HT5 receptors
-
申请号： US10590265申请日： 2005-02-15
-
公开(公告)号： US08431604B2公开(公告)日： 2013-04-30
- 发明人: Astrid Netz , Wilhelm Amberg , Udo Lange , Michael Ochse , Charles W. Hutchins , Francisco-Xavier Garcia-Ladona , Wolfgang Wernet , Andreas Kling
- 申请人： Astrid Netz , Wilhelm Amberg , Udo Lange , Michael Ochse , Charles W. Hutchins , Francisco-Xavier Garcia-Ladona , Wolfgang Wernet , Andreas Kling
- 申请人地址： DE Wiesbaden
- 专利权人： Abbott GmbH & Co. KG
- 当前专利权人： Abbott GmbH & Co. KG
- 当前专利权人地址： DE Wiesbaden
- 代理机构： MIchael Best & Friedrich LLP
- 代理商 Lisa V. Mueller
- 优先权： DE102004008141 20040219
- 国际申请： PCT/EP2005/001521 WO 20050215
- 国际公布： WO2005/082871 WO 20050909
- 主分类号： A61K31/155
- IPC分类号： A61K31/155 ; A61K31/421 ; A61P19/02 ; C07D263/30 ; C07D277/20
摘要：
The present invention relates to guanidine compounds of the general formula I corresponding enantiomeric, diastereomeric and/or tautomeric forms thereof as well as pharmaceutically acceptable salts thereof. The present compound further relates to the use of guanidine compounds as binding partners for 5-HT5 receptors for the treatment of diseases which are modulated by a 5-HT5 receptor activity, in particular for the treatment of neurodegenerative and neuropsychiatric disorders as well as the associated signs, symptoms and dysfunctions.
公开/授权文献
信息查询
