The invention relates to a dispenser (1) for pulverulent substances (30), in particular medicaments, from a blister pack (25), dome-shaped cavities (26) of which that are disposed on a base layer (28) can, by movement in a dispenser housing (4), be brought step by step into an emptying position, in which they can be opened by means of a needle (31) and can be emptied by a suction air stream (a) leading to a mouthpiece (6). To achieve optimum emptying of the cavities, it is proposed that the needle (31) passes crosswise through both lateral walls of the dome (29) of the cavities (preferably parallel to the base layer 28) in order to form a through path to the mouthpiece for suction air.