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发明授权
US08435748B2 Method for monitoring, diagnosing, and screening cancer through measuring the concentration of des-R prothrombin activation peptide fragment F2 (des-R F2) in a serum 有权
通过测定血清中des-R凝血酶原活化肽片段F2（des-R F2）的浓度来监测，诊断和筛选癌症的方法

Method for monitoring, diagnosing, and screening cancer through measuring the concentration of des-R prothrombin activation peptide fragment F2 (des-R F2) in a serum
摘要：
The present invention relates to a method for diagnosis and screening of cancer by measuring the expression of des-R prothrombin activation peptide fragment F2 (des-R F2) in serum, more precisely, des-R-prothrombin activation peptide fragment F2 which is the protein marker down-regulated specifically in liver cancer, breast cancer, and stomach cancer, and a method for diagnosis and screening of liver cancer, breast cancer, and stomach cancer by quantifying the protein marker. The protein marker of the present invention can be effectively used for diagnosis and screening of liver cancer, breast cancer and stomach cancer by comparing the expression of the said protein marker in a normal subject with that of a liver cancer, breast cancer, or stomach cancer patients.
摘要（中）：

本发明涉及一种通过测定血清中des-R凝血酶原活化肽片段F2（des-R F2）的表达，更确切地说，des-R-凝血酶原活化肽片段F2的表达来诊断和筛选癌症的方法， 特异性下调肝癌，乳腺癌和胃癌的蛋白质标记，以及通过量化蛋白质标记物来诊断和筛选肝癌，乳腺癌和胃癌的方法。 通过比较正常对象中所述蛋白质标记物与肝癌，乳腺癌或胃癌的蛋白质标记物的表达，本发明的蛋白质标记物可以有效地用于肝癌，乳腺癌和胃癌的诊断和筛选 耐心。

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