发明授权
US08436001B2 Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use 有权
吡唑-4-基 - 杂环基甲酰胺化合物及其使用方法

Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use
摘要:
Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is a thiazolyl, picolinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
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