发明授权
- 专利标题: MST1 kinase inhibitors and methods of their use
- 专利标题(中): MST1激酶抑制剂及其使用方法
-
申请号: US13410407申请日: 2012-03-02
-
公开(公告)号: US08440652B2公开(公告)日: 2013-05-14
- 发明人: David John Augeri , Jeffrey Thomas Bagdanoff , Simon David Peter Baugh , Marianne Carlsen , Kenneth Gordon Carson , John Anthony Gilleran , Wei He , Tamas Oravecz , Konstantin Salojin , Leonard Sung
- 申请人: David John Augeri , Jeffrey Thomas Bagdanoff , Simon David Peter Baugh , Marianne Carlsen , Kenneth Gordon Carson , John Anthony Gilleran , Wei He , Tamas Oravecz , Konstantin Salojin , Leonard Sung
- 申请人地址: US TX The Woodlands
- 专利权人: Lexicon Pharmaceuticals, Inc.
- 当前专利权人: Lexicon Pharmaceuticals, Inc.
- 当前专利权人地址: US TX The Woodlands
- 代理商 Max Bachrach
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; C07D495/04 ; A61K31/4418 ; A61K31/444
摘要:
Compounds for the inhibition of mammalian Ste20-like kinase 1 (MST1) are disclosed, along with compositions comprising them and methods of their use in the treatment, management or prevention of an inflammatory or autoimmune diseases or disorders. Particular compounds are of the formula:
公开/授权文献
- US20120225857A1 MST1 KINASE INHIBITORS AND METHODS OF THEIR USE 公开/授权日:2012-09-06
信息查询