发明授权
- 专利标题： Deacetylase inhibitors and uses thereof
- 专利标题（中）： 脱乙酰酶抑制剂及其用途
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申请号： US13055241申请日： 2009-07-22
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公开(公告)号： US08440716B2公开(公告)日： 2013-05-14
- 发明人: Weiping Tang , James Elliot Bradner , Stuart L. Schreiber
- 申请人： Weiping Tang , James Elliot Bradner , Stuart L. Schreiber
- 申请人地址： US MA Cambridge US MA Boston
- 专利权人： President and Fellows of Harvard College,Dana-Farber Cancer Institute, Inc.
- 当前专利权人： President and Fellows of Harvard College,Dana-Farber Cancer Institute, Inc.
- 当前专利权人地址： US MA Cambridge US MA Boston
- 代理机构： Wolf, Greenfield & Sacks, P.C.
- 代理商 C. Hunter Baker
- 国际申请： PCT/US2009/004235 WO 20090722
- 国际公布： WO2010/011296 WO 20100128
- 主分类号： A61K31/24
- IPC分类号： A61K31/24 ; A61K31/195 ; A61K31/165 ; C07C229/02 ; C07C251/00 ; C07C233/88
摘要：
The present invention provides novel compounds of formula (I) and pharmaceutical compositions thereof. The inventive compounds are useful as deacetylase inhibitors (e.g., histone deacetylase inhibitors) and may be useful in the treatment of proliferative diseases such as cancer. In particular, the inventive compounds are HDAC6 inhibitors. The invention also provide synthetic methods for preparing the inventive compounds.
公开/授权文献
- US20110172303A1 DEACETYLASE INHIBITORS AND USES THEREOF 公开/授权日：2011-07-14
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