- 专利标题： Antioxidant inflammation modulators: oleanolic acid derivatives with amino acid and other modifications at C-17
-
申请号： US13356455申请日： 2012-01-23
-
公开(公告)号： US08440854B2公开(公告)日： 2013-05-14
- 发明人: Eric Anderson , Xin Jiang , Melean Visnick
- 申请人： Eric Anderson , Xin Jiang , Melean Visnick
- 申请人地址： US TX Irving
- 专利权人： Reata Pharmaceuticals, Inc.
- 当前专利权人： Reata Pharmaceuticals, Inc.
- 当前专利权人地址： US TX Irving
- 代理机构： Parker Highlander PLLC
- 主分类号： C07D333/32
- IPC分类号： C07D333/32 ; C07D307/02 ; C07D231/00 ; C07D211/06 ; C07D265/30 ; C07C255/47 ; A31K31/38 ; A31K31/445 ; A31K31/415 ; A31K31/535 ; A31K31/34 ; A31K31/27
摘要：
This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.