Provided is an image interpolation method and apparatus using a reference block depending on a direction. The image interpolation method may generate a horizontal reference block and a vertical reference block each with respect to an inputted image, and determine interpolation directivity with respect to the inputted image using the generated horizontal reference block and vertical reference block, thereby performing an interpolation on an image based on accurate interpolation directivity. In particular, the image interpolation method may determine whether to verify interpolation directivity depending on an edge intensity of an inputted image, thereby performing a color filter array (CFA) interpolation on an image based on an edge direction without determining the interpolation directivity, when the edge intensity is strong.