发明授权
- 专利标题: Inhibitors of beta-secretase
- 专利标题(中): β-分泌酶抑制剂
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申请号: US13059879申请日: 2009-08-14
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公开(公告)号: US08450308B2公开(公告)日: 2013-05-28
- 发明人: Lawrence W. Dillard , Jing Yuan , Lanqi Jia , Yajun Zheng
- 申请人: Lawrence W. Dillard , Jing Yuan , Lanqi Jia , Yajun Zheng
- 申请人地址: US PA Fort Washington
- 专利权人: Vitae Pharmaceuticals, Inc.
- 当前专利权人: Vitae Pharmaceuticals, Inc.
- 当前专利权人地址: US PA Fort Washington
- 代理机构: McCarter & English, LLP
- 代理商 Steven G. Davis
- 国际申请: PCT/US2009/004686 WO 20090814
- 国际公布: WO2010/021680 WO 20100225
- 主分类号: C07D311/94
- IPC分类号: C07D311/94 ; C07D239/00 ; C07D487/10 ; C07D279/04 ; A61K31/547 ; A61K31/4166 ; A61K31/4168 ; A61K31/4178 ; A61K31/438 ; A61K31/505
摘要:
The present invention is directed to a compound represented by the following structural formula: or a pharmaceutically acceptable salt thereof. Pharmaceutical composition comprising a compound represented by Structural Formula (I) and method of use of these compound for inhibiting BACE activity in a subject in need of such treatment are also described.
公开/授权文献
- US20110218192A1 Inhibitors Of Beta-Secretase 公开/授权日:2011-09-08
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