发明授权
- 专利标题: Compound
- 专利标题(中): 复合
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申请号: US12821711申请日: 2010-06-23
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公开(公告)号: US08450462B2公开(公告)日: 2013-05-28
- 发明人: Satoshi Ogawa , Fumio Yamauchi , Kengo Kanazaki , Mayuko Kishi
- 申请人: Satoshi Ogawa , Fumio Yamauchi , Kengo Kanazaki , Mayuko Kishi
- 申请人地址: JP Tokyo
- 专利权人: Canon Kabushiki Kaisha
- 当前专利权人: Canon Kabushiki Kaisha
- 当前专利权人地址: JP Tokyo
- 代理机构: Canon U.S.A., Inc., IP Division
- 优先权: JP2009-152611 20090626; JP2010-109288 20100511
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; C07K16/46 ; A61K49/06 ; A61K49/16 ; A61K49/22
摘要:
A compound including a polymer is represented by general formula (1): L-Y-A (1) wherein, A is a single-chain antibody moiety, which is a polypeptide including an antigen-binding site, L is a linker moiety, which is a polypeptide including a protease cleavage site, Y is a peptide moiety, which includes 0 or more amino acids connecting the linker moiety L with the single-chain antibody moiety A, and the linker moiety L binds to an N terminus of the peptide moiety Y or an N terminus of the single-chain antibody moiety A.
公开/授权文献
- US20110064666A1 COMPOUND 公开/授权日:2011-03-17
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