发明授权
- 专利标题： Viral chemokine-antigen fusion proteins
- 专利标题（中）： 病毒趋化因子 - 抗原融合蛋白
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申请号： US13541997申请日： 2012-07-05
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公开(公告)号： US08460675B2公开(公告)日： 2013-06-11
- 发明人: Larry W. Kwak , Bira Arya
- 申请人： Larry W. Kwak , Bira Arya
- 申请人地址： US DC Washington
- 专利权人： The United States of America, as represented by the Secretary, Department of the Health and Human Services
- 当前专利权人： The United States of America, as represented by the Secretary, Department of the Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Klarquist Sparkman, LLP
- 主分类号： A61K39/12
- IPC分类号： A61K39/12 ; A61K38/00 ; A61K45/00 ; A61K39/00 ; A61K31/00 ; C08H1/00
摘要：
The present invention relates to a vaccine for increasing the immunogenicity of a tumor antigen thus allowing treatment of cancer, as well as a vaccine that increases the immunogenicity of a viral antigen, thus allowing treatment of viral infection, including immunodeficiency virus (HIV) infection. In particular, the present invention provides a fusion protein comprising a viral chemokine fused to either a tumor antigen or viral antigen which is administered as either a protein or nucleic acid vaccine to elicit an immune response effective in treating cancer or effective in treating or preventing viral infection.
公开/授权文献
- US20120276101A1 VIRAL CHEMOKINE-ANTIGEN FUSION PROTEINS 公开/授权日：2012-11-01
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