发明授权
- 专利标题: Heterocyclic derivative and use thereof
- 专利标题(中): 杂环衍生物及其用途
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申请号: US12936291申请日: 2009-04-03
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公开(公告)号: US08461348B2公开(公告)日: 2013-06-11
- 发明人: Nobuyuki Matsunaga , Yoshihisa Nakada , Yusuke Ohba , Hideyuki Nakagawa
- 申请人: Nobuyuki Matsunaga , Yoshihisa Nakada , Yusuke Ohba , Hideyuki Nakagawa
- 申请人地址: JP Osaka
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人地址: JP Osaka
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP2008-098622 20080404
- 国际申请: PCT/JP2009/056994 WO 20090403
- 国际公布: WO2009/123316 WO 20091008
- 主分类号: C07D277/20
- IPC分类号: C07D277/20 ; C07D277/62 ; A61K31/425
摘要:
The present invention aims to provide a compound having superior pharmacological action, physicochemical properties and the like and useful as an sGC activation drug, or an agent for the prophylaxis and/or treatment of diseases such as hypertension, ischemic cardiac disease, cardiac failure, kidney disease, arteriosclerotic disease, atrial fibrillation, pulmonary hypertension, diabetes, diabetic complications, metabolic syndrome, peripheral arterial obstruction, erectile dysfunction and the like.An sGC activation drug containing a compound represented by the formula (II): wherein each symbol is as defined in the specification, or a salt thereof, as an active ingredient.
公开/授权文献
- US20110028493A1 HETEROCYCLIC DERIVATIVE AND USE THEREOF 公开/授权日:2011-02-03