A method for gesture-based distribution of files may include 1) receiving, at a first computing device, input that identifies a file for gesture-based distribution to one or more other computing devices; 2) detecting a plurality of additional computing devices in physical proximity of the first computing device; 3) for each computing device in the plurality of additional computing devices, determining a physical location of the additional computing device; 4) detecting, on the first computing device, a gesture of a user of the first computing device; 5) determining, based on one or more of the physical locations of the additional computing devices, that the gesture of the user was directed toward one or more of the additional computing devices; 6) distributing the file to the one or more additional computing devices toward which the user gestured. Various other methods, systems, and computer-readable media are also disclosed.