- 专利标题: 1,2-disubstituted heterocyclic compounds
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申请号: US13290527申请日: 2011-11-07
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公开(公告)号: US08466148B2公开(公告)日: 2013-06-18
- 发明人: Amy Ripka , Gideon Shapiro , Richard Chesworth
- 申请人: Amy Ripka , Gideon Shapiro , Richard Chesworth
- 申请人地址: US MA Watertown
- 专利权人: EnVivo Pharmaceuticals, Inc.
- 当前专利权人: EnVivo Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Watertown
- 代理机构: Wilmer Cutler Pickering Hale and Dorr LLP
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; A61K31/4709 ; C07D413/14 ; C07D417/14 ; C07D417/12 ; C07D405/12 ; C07D401/02 ; C07D405/14
摘要:
1,2-disubstituted heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described. Also described are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Among the disorders which may be treated are neurological, neurodegenerative and psychiatric disorders including, but not limited to, those associated with cognitive deficits or schizophrenic symptoms.
公开/授权文献
- US20120232265A1 1,2-Disubstituted Heterocyclic Compounds 公开/授权日:2012-09-13