发明授权
- 专利标题： Manipulation of beads in droplets and methods for splitting droplets
- 专利标题（中）： 小滴处理珠粒和分裂液滴的方法
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申请号： US12761147申请日： 2010-04-15
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公开(公告)号： US08470606B2公开(公告)日： 2013-06-25
- 发明人: Vijay Srinivasan , Vamsee K. Pamula , Michael G. Pollack , Richard B. Fair
- 申请人： Vijay Srinivasan , Vamsee K. Pamula , Michael G. Pollack , Richard B. Fair
- 申请人地址： US NC Durham US NC Research Triangle Park
- 专利权人： Duke University,Advanced Liquid Logic Inc.
- 当前专利权人： Duke University,Advanced Liquid Logic Inc.
- 当前专利权人地址： US NC Durham US NC Research Triangle Park
- 代理机构： Ward & Smith, P.A.
- 代理商 William A. Barrett
- 主分类号： G01N15/06
- IPC分类号： G01N15/06 ; G01N33/00 ; G01N33/48
摘要：
The invention provides a method of circulating magnetically responsive beads within a droplet in a droplet actuator. The invention also provides methods for splitting droplets. The invention, in one embodiment, makes use of a droplet actuator with top and bottom substrates, a plurality of magnetic fields respectively present proximate the top and bottom substrates, wherein at least one of the magnet fields is selectively alterable, and a plurality of droplet operations electrodes positioned along at least one of the top and bottom surfaces. A droplet is positioned between the top and bottom surfaces and at least one of the magnetic fields is selectively altered.